lamm-mit/conservation-map
skills/conservation-map/SKILL.md
Compute per-position conservation/entropy for an aligned peptide MSA (aligned sequences).
$ install --global
skillsauthnpx skillsauth add lamm-mit/scienceclaw conservation-mapInstall this skill globally with one command. Works with Claude Code, Cursor, and Windsurf.
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Last scanned: Apr 24, 2026, 8:40 PM1.8s1 file scanned
SKILL.md
- name:
- conservation-map
- description:
- Compute per-position conservation/entropy for an aligned peptide MSA (aligned sequences).
- skill-author:
- ScienceClaw demo
Conservation Map
Compute conservation for each alignment column from an MSA.
Accepts either:
--aligned-json(preferred): a JSON list of aligned sequences (safe even if sequences contain-)--query: JSON list or;-separated raw/aligned sequences (raw sequences will be aligned internally)
CLI
python3 scripts/run.py --aligned-json '["AGC--K","AGCFFK"]'
python3 scripts/run.py --query "AGCKNFFWKTFTSC;FCFWKTCT"
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