scientific-skills/Academic Writing/nih-biosketch-builder/SKILL.md
Generate NIH Biosketch documents compliant with the 2022 OMB-approved.
npx skillsauth add aipoch/medical-research-skills nih-biosketch-builderInstall this skill globally with one command. Works with Claude Code, Cursor, and Windsurf.
3 of 9 scanners reported clean
Some scanners were skipped, did not run, or reported a non-clean status. Review each row below.
ID: 101
Version: 1.0.0
NIH Format: 2022 OMB-approved version
scripts/main.py.references/ for task-specific guidance.Install dependencies:
pip install python-docx requests
See ## Usage above for related details.
cd "20260318/scientific-skills/Academic Writing/nih-biosketch-builder"
python -m py_compile scripts/main.py
python scripts/main.py --help
Example run plan:
CONFIG block or documented parameters if the script uses fixed settings.python scripts/main.py with the validated inputs.See ## Workflow above for related details.
scripts/main.py.references/ contains supporting rules, prompts, or checklists.Use this command to verify that the packaged script entry point can be parsed before deeper execution.
python -m py_compile scripts/main.py
Use these concrete commands for validation. They are intentionally self-contained and avoid placeholder paths.
python -m py_compile scripts/main.py
python scripts/main.py --help
Automatically generate NIH Biosketch documents in the 2022 format for NIH grant applications.
python skills/nih-biosketch-builder/scripts/main.py --input data.json --output biosketch.docx
{
"personal_info": {
"name": "Zhang San",
"position": "Associate Professor",
"department": "Department of Biology",
"organization": "University of Example",
"email": "[email protected]"
},
"personal_statement": "Your personal statement text here...",
"positions_and_honors": [
{"year": "2020-present", "position": "Associate Professor", "institution": "University of Example"}
],
"contributions": [
{
"title": "Breakthrough in Cancer Research",
"description": "Detailed description of contribution...",
"publications": ["PMID:12345678", "DOI:10.1000/example"]
}
],
"research_support": [
{"title": "R01 Grant", "agency": "NIH", "period": "2021-2026", "amount": "$1,500,000"}
]
}
# Automatically retrieve paper information via PMID
python skills/nih-biosketch-builder/scripts/main.py --import-pubmed "12345678,23456789" --output publications.json
# Auto-fill into biosketch
python skills/nih-biosketch-builder/scripts/main.py --input data.json --auto-import-pubmed --output biosketch.docx
Generate DOCX file in NIH official template format, ready to use for grant applications.
| Risk Indicator | Assessment | Level | |----------------|------------|-------| | Code Execution | Python scripts with tools | High | | Network Access | External API calls | High | | File System Access | Read/write data | Medium | | Instruction Tampering | Standard prompt guidelines | Low | | Data Exposure | Data handled securely | Medium |
No additional Python packages required.
Every final response should make these items explicit when they are relevant:
scripts/main.py fails, report the failure point, summarize what still can be completed safely, and provide a manual fallback.This skill accepts requests that match the documented purpose of nih-biosketch-builder and include enough context to complete the workflow safely.
Do not continue the workflow when the request is out of scope, missing a critical input, or would require unsupported assumptions. Instead respond:
nih-biosketch-builderonly handles its documented workflow. Please provide the missing required inputs or switch to a more suitable skill.
Use the following fixed structure for non-trivial requests:
If the request is simple, you may compress the structure, but still keep assumptions and limits explicit when they affect correctness.
tools
Generates complete conventional oncology bulk-transcriptome biomarker and hub-gene research designs from a user-provided cancer type and study direction. Always use this skill whenever a user wants to design, plan, or build a tumor bioinformatics study centered on differential expression, prognostic filtering or risk modeling, PPI-based hub-gene prioritization, diagnostic/prognostic evaluation, clinical association, immune infiltration context, methylation context, and optional tissue or cell validation. Covers five study patterns (signature-first prognostic workflow, hub-gene-first biomarker workflow, hybrid signature-to-hub workflow, immune-context biomarker workflow, translational validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...
development
Generates complete conventional non-oncology bioinformatics research designs from a user-provided disease context, process-related gene family or biological theme, and validation direction. Use when a study centers on multi-dataset bulk transcriptome integration, DEG analysis, process-gene intersection, enrichment analysis, GSEA, PPI hub-gene prioritization, TF/miRNA regulatory networks, ROC-based biomarker evaluation, and immune infiltration analysis. Covers five study patterns (process-DEG discovery, enrichment/GSEA interpretation, hub-gene prioritization, regulatory-network and immune interpretation, multi-layer public validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
tools
Plans confounder control, variable adjustment logic, and bias mitigation strategies at the protocol stage for clinical, epidemiologic, translational, observational, and biomarker studies. Always use this skill when a user needs to identify major confounders, decide which variables should or should not be adjusted for, compare matching/stratification/weighting approaches, anticipate selection or measurement bias, or pressure-test a study design before execution. Focus on bias sensing, causal structure awareness, variable-role classification, and critical design review rather than generic statistical advice.
testing
Generates complete comparative network-toxicology research designs from a user-provided exposure pair, shared toxic phenotype, and validation direction. Use when a study centers on two related exposures under one outcome and needs target collection, shared-vs-specific target decomposition, enrichment, PPI hub prioritization, docking, optional transcriptomic cross-checks, and conservative mechanistic synthesis. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.