
Identify grammar, logical, and flow errors in text and suggest targeted fixes without rewriting the entire text. Use when proofreading content, checking writing quality, or reviewing a draft.
Structured hypothesis formulation from observations. Use when you have experimental observations or data and need to formulate testable hypotheses with predictions, propose mechanisms, and design experiments to test them. Follows scientific method framework. For open-ended ideation use scientific-brainstorming; for automated LLM-driven hypothesis testing on datasets use hypogenic.
Design, create, and revise Google Sheets charts with better chart-spec recall and editing discipline. Use when the user wants to add a chart to a sheet, choose the right chart type for existing data, repair a broken chart, update a chart's data series, or reposition or resize a chart after creating it.
Create publication-quality scientific diagrams using Nano Banana 2 AI with smart iterative refinement. Uses Gemini 3.1 Pro Preview for quality review. Only regenerates if quality is below threshold for your document type. Specialized in neural network architectures, system diagrams, flowcharts, biological pathways, and complex scientific visualizations.
Deep multi-source research combining academic MCPs (arxiv, semantic-scholar, paper-search, deepwiki), Exa semantic search, and local ~/.topos knowledge base. Use for comprehensive research requiring multiple sources. NEVER fall back to web_search - ask user for help instead.
Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).
Statistical test selection, assumption checking, and APA-formatted reporting. Use when analyzing experimental results or writing results sections.
Automated generation of baseline characteristics tables (Table 1) for clinical research papers.
Apply statistical methods including descriptive stats, trend analysis, outlier detection, and hypothesis testing. Use when analyzing distributions, testing for significance, detecting anomalies, computing correlations, or interpreting statistical results.
Automated web research for peptides, biohacking protocols, longevity science, and trending health topics. Use when you need to discover new information, track emerging trends, monitor scientific updates, or generate content ideas based on current research. Runs periodically via heartbeat or on-demand.
Statistical power analysis and sample size determination
Fetch academic papers from Sci-Hub given a DOI. Automatically downloads PDFs and saves them to research/papers/ with clean filenames. Use when the user provides a DOI or requests a paper from PubMed.
Professional beautification tool for gene expression heatmaps, automatically adds clustering trees, color annotation tracks, and intelligently optimizes label layout.
This skill should be used when the user asks for "deep research", "research team", "comprehensive analysis", "research report", "investigate thoroughly", "compare X vs Y in depth", or needs synthesis across multiple sources with verification. It spawns a coordinated team of researcher agents across multiple rounds, with the lead triaging findings and creating targeted follow-up tasks. Scales from Focused (2 researchers, 1-2 rounds) to Comprehensive (4 researchers, 3-4 rounds with cross-verification). Do NOT use for simple lookups, debugging, or questions answerable with 1-2 searches.
Professional LaTeX writing assistant. Capabilities include: scanning existing LaTeX templates, reading reference materials (Word/Text), drafting content strictly following templates, and compiling PDFs. Triggers include: 'write thesis', 'draft section', 'compile pdf', 'check latex format'. Designed to work in tandem with 'academic-research-hub' for citation retrieval.
Manage citations systematically throughout the research and writing process.
Evaluate scientific claims and evidence quality. Use for assessing experimental design validity, identifying biases and confounders, applying evidence grading frameworks (GRADE, Cochrane Risk of Bias), or teaching critical analysis. Best for understanding evidence quality, identifying flaws. For formal peer review writing use peer-review.
Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies
Statistical models library for Python. Use when you need specific model classes (OLS, GLM, mixed models, ARIMA) with detailed diagnostics, residuals, and inference. Best for econometrics, time series, rigorous inference with coefficient tables. For guided statistical test selection with APA reporting use statistical-analysis.
Applies cognitive science frameworks for creative thinking to CS and AI research ideation. Use when seeking genuinely novel research directions by leveraging combinatorial creativity, analogical reasoning, constraint manipulation, and other empirically grounded creative strategies.
Transparent, rigorous research with full methodology — not a black-box API wrapper. Conducts exhaustive investigation through mandated 2-cycle research per theme, APA 7th citations, evidence hierarchy, and 3 user checkpoints. Self-contained using native OpenClaw tools (web_search, web_fetch, sessions_spawn). Use for literature reviews, competitive intelligence, or any research requiring academic rigor and reproducibility.
Use this skill when the user requests to review, analyze, critique, or summarize academic papers, research articles, preprints, or scientific publications. Supports comprehensive structured reviews covering methodology assessment, contribution evaluation, literature positioning, and constructive feedback generation. Trigger on queries involving paper URLs, uploaded PDFs, arXiv links, or requests like "review this paper", "analyze this research", "summarize this study", or "write a peer review".
Run autonomous research tasks that plan, search, read, and synthesize information into comprehensive reports.
Comprehensive research assistant that synthesizes information from multiple sources with citations. Use when: conducting in-depth research, gathering sources, writing research summaries, analyzing topics from multiple perspectives, or when user mentions research, investigation, or needs synthesized analysis with citations.
Systematic peer review toolkit. Evaluate methodology, statistics, design, reproducibility, ethics, figure integrity, reporting standards, for manuscript and grant review across disciplines.
Beautify meta-analysis forest plots with customizable odds ratio points and confidence intervals
Find and compile academic literature with citation lists across Google Scholar, PubMed, arXiv, IEEE, ACM, Semantic Scholar, Scopus, and Web of Science. Use for requests like “find related literature,” “related work,” “citation list,” or “key papers on a topic.”
Monte Carlo methods for uncertainty quantification
Meta-agent supervisor that manages a fleet of Claude Code agents running in tmux windows. Auto-discovers spare worktrees, spawns agents, monitors state, kicks idle agents, approves safe confirmations, and recycles worktrees when done. TRIGGER when user asks to supervise agents, run parallel tasks, manage worktrees, check agent status, or orchestrate parallel work.
Regression Analysis Helper - Auto-activating skill for Data Analytics. Triggers on: regression analysis helper, regression analysis helper Part of the Data Analytics skill category.
Presentation creation, editing, and analysis. When Claude needs to work with presentations (.pptx files) for: (1) Creating new presentations, (2) Modifying or editing content, (3) Working with layouts, (4) Adding comments or speaker notes, or any other presentation tasks
Build complex Boolean query strings for precise PubMed/MEDLINE literature retrieval. Trigger when user needs MeSH term mapping, Boolean query construction, advanced PubMed filters, citation searching, systematic review search strategy, or clinical query optimization.
Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management. For Python workflows, prefer biopython (Bio.Entrez). Use this for direct HTTP/REST work or custom API implementations.
Standard single-cell RNA-seq analysis pipeline. Use for QC, normalization, dimensionality reduction (PCA/UMAP/t-SNE), clustering, differential expression, and visualization. Best for exploratory scRNA-seq analysis with established workflows. For deep learning models use scvi-tools; for data format questions use anndata.
Robust statistical methods resistant to outliers
Build slide decks and presentations for research talks. Use this for making PowerPoint slides, conference presentations, seminar talks, research presentations, thesis defense slides, or any scientific talk. Provides slide structure, design templates, timing guidance, and visual validation. Works with PowerPoint and LaTeX Beamer.
Use scipy.optimize.curve_fit for nonlinear least squares parameter estimation from experimental data.
Recommends appropriate statistical methods (T-test vs ANOVA, etc.) based.
Configure and manage - Calculate statistical significance calculator operations. Auto-activating skill for Data Analytics. Triggers on: statistical significance calculator, statistical significance calculator Part of the Data Analytics skill category. Use when working with statistical significance calculator functionality. Trigger with phrases like "statistical significance calculator", "statistical calculator", "statistical".